Behavior of 125I-rabbit factor XI in Watanabe-hereditable hyperlipidemic rabbit(WHHL rabbit).
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چکیده
منابع مشابه
Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.
The effects of trandolapril (0.25 mg/kg body wt per 48 hours) on aortic atherosclerosis were examined in the Watanabe heritable hyperlipidemic rabbit treated from 3 to 12 months of age. Trandolapril caused a significant decrease in atherosclerotic involvement of the intimal surface of total aorta from 56.3 +/- 5.0% in control Watanabe rabbits to 35.0 +/- 4.1% with treatment (p less than 0.01). ...
متن کاملApoVLDL of the Watanabe Heritable Hyperlipidemic rabbit and the cholesterol-fed rabbit.
The Watanabe Heritable Hyperlipidemic rabbit (WHHL rabbit) and the cholesterol-fed rabbit have been reported to show elevations of very low density (VLDL), intermediate density (IDL), and low density lipoproteins (LDL), and a broad-beta band on agarose-gel electrophoresis. We have studied the lipid and lipoprotein composition of WHHL rabbits and cholesterol-fed rabbits using ultracentrifugal an...
متن کاملCorrection of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.
Familial hypercholesterolemia is an inherited disease in humans that is caused by a defect in the receptor for low density lipoproteins (LDLR). The existence of an animal model for this disease, the Watanabe heritable hyperlipidemic (WHHL) rabbit, makes it an attractive candidate for developing new therapies that involve gene transfer into liver. As a first step toward the development of these ...
متن کاملSocial environment influences the progression of atherosclerosis in the watanabe heritable hyperlipidemic rabbit.
BACKGROUND Although there is evidence that emotionally stressful behavior can accelerate the progression of atherosclerosis, there is less data to support the notion that affiliative social behavior can slow disease progression. The present study examines the influence of social environment on the progression of atherosclerosis in the Watanabe Heritable Hyperlipidemic (WHHL) rabbit, a model tha...
متن کاملEffect of fish oil on atherogenesis in Watanabe heritable hyperlipidemic rabbit.
The effect of dietary supplementation with fish oil was investigated in the Watanabe heritable hyperlipidemic (WHHL) rabbit. Rabbits were fed Maxepa (1 g/kg body weight) from weaning for a 6-month period and were compared to controls. Fish oil supplements resulted in significant decreases in plasma triglyceride and cholesterol at 4 weeks after the start of the study, and these differences persi...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1988
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.19.208